Fig. 2

CBB pathway enzymatic steps predicted to positively influence flux control [31, 70, 72, 73, 77, 78]. Pathway intermediates: DHAP, dihydroxyacetone phosphate; FBP, fructose-1,6-bisphosphate; G3P, glyceraldehyde-3-phosphate; Pi, pyrophosphate; S7P, sedoheptulose-7-phosphate; SBP, sedoheptulose-1,7-bisphosphate; Xu5P, xylulose-5-phosphate. Enzymes/genes: fba, fructose-bisphosphate aldolase; SBPase, sedoheptulose-1,7-bisphosphatase; tkl, transketolase. The remaining pathway intermediates and enzymes are defined in Fig. 1 legend. The crystal structures of RuBisCO, SBPase, tkl and fba were generated in Chimera [79] using pdb accession codes 6hbc, 3oi7, 1trk and 1rv8, respectively (https://www.rcsb.org/)