Fig. 1

Time series of sugarcane bagasse hydrolysate fermentation with dynamic modelling. Green dots correspond to in vivo fermentation data. Purple dashed vertical lines indicate timepoints chosen for transcriptome analysis. Purple triangles correspond to data from cultures used for transcriptome sampling. Solid brown lines represent in silico data from a simulation with citric output constrained to fit the in vivo data. A Change in biomass dry weight (g/L) over time. B Change in external phosphate concentration (g/L) over time. C Change in external citric acid concentration (g/L) over time. Dashed brown line represents in silico data from a simulation with unconstrained citric output. D Change in external glucose concentration (g/L) over time. E Change in external xylose concentration (g/L) over time. Individual data-points are shown