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Table 5 Input/output fluxes in iDU1327 at selected timepoints with citric output constrained in line with in vivo data

From: Integration of Aspergillus niger transcriptomic profile with metabolic model identifies potential targets to optimise citric acid production from lignocellulosic hydrolysate

Input/output reaction

T1 flux (mmol gDW−1 h−1)

T2 flux (mmol gDW−1 h−1)

T3 flux (mmol gDW−1 h−1)

Glucose (DGLCe <==>)

− 1.2552

− 0.4392

0.0

Xylose (XYLe <==>)

− 0.0718

− 0.0647

− 0.1936

External phosphate (PIe <==>)

− 0.1455

0.0

0.0

Internal phosphate (PI <==>)

0.1339

− 0.0019

− 0.00005

Biomass

0.1207 (h−1)

0.0195 (h−1)

0.0006 (h−1)

Citric acid (CIT-e <==>)

0.0

0.12

0.12

Carbon dioxide (CO2e <==>)

3.3671

1.5066

0.2268

Oxygen (O2e <==>)

− 1.9835

− 1.4626

− 0.4004