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Table 7 Kinetic parameters applied in dynamic modelling of sugarcane bagasse hydrolysate fermentation

From: Integration of Aspergillus niger transcriptomic profile with metabolic model identifies potential targets to optimise citric acid production from lignocellulosic hydrolysate

Parameter

Description

Value

\(v_{{Pe,{\text{max}}}}\) (mmol gDW−1 h−1)

External phosphate maximum input rate

0.15

\(K_{Pe}\) (mM)

External phosphate Michaelis constant

0.0333a

\(v_{{P,{\text{max}}}}\) (mmol gDW−1 h−1)

Internal phosphate maximum input rate

0.06

\(K_{P}\) (mM)

Internal phosphate Michaelis constant

20

\(v_{G1}\) (mmol gDW−1 h−1)

External glucose passive uptake rate

0.0027 × [GLC]b

\(v_{{G2,{\text{max}}}}\) (mmol gDW−1 h−1)

External glucose transport-mediated uptake maximum rate

0.08

\(K_{G2}\) (mM)

External glucose transport-mediated uptake Michaelis constant

0.26a

\(K_{i2}\) (mM)

External glucose transport-mediated uptake citrate inhibition constant

933a

\(v_{X1 }\) (mmol gDW−1 h−1)

External xylose passive uptake rate

0.00027 × [XYL]c

\(v_{{X2,{\text{max}}}}\) (mmol gDW−1 h−1)

External xylose transport-mediated uptake maximum rate

0.18

\(K_{X2}\) (mM)

External xylose transport-mediated uptake Michaelis constant

3.33a

\(v_{{{\text{CIT}}}}\) (mmol gDW−1 h−1)

Citric acid output rate constraintd

0.12a

  1. aThese values are the same as in the dynamic modelling reported previously [17]
  2. b[GLC] is the concentration of external glucose in mM
  3. c[XYL] is the concentration of external xylose in mM
  4. dCitric acid output rate constraint was only applied 32 h after the start time