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Fig. 2 | Biotechnology for Biofuels and Bioproducts

Fig. 2

From: In silico-guided metabolic engineering of Bacillus subtilis for efficient biosynthesis of purine nucleosides by blocking the key backflow nodes

Fig. 2

Applications of the genome-scale metabolic network models (GEM) to predict the optimal targets. a The minimum medium design through GEM. The minimum medium was designed in the B. subtilis model for the simulation calculation. b Analysis of IMP flux and Biomass flux by FBA. c Prediction of the potential targets by GDLS. d Flow disturbance analysis of the mutants by ROOM. Maximal and minimal IMP production rates were predicted at different growth rates

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Biotechnology for Biofuels and Bioproducts

ISSN: 2731-3654

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