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Table 3 Comparison of AC production by different B. subtilis

From: Acetoin production from lignocellulosic biomass hydrolysates with a modular metabolic engineering system in Bacillus subtilis

Strain

Method

Substrate

Concentration

(g/L)

Yield

(g/g)

Refs.

B. subtilis 168/pMA5-zwf

Overexpression of glucose-6-phosphate dehydrogenase in B. subtilis 168

Glucose

43.3

0.323

[45]

B. subtilis

BSUW06

Deletion of bdhA, acoA, and pta, and overexpression of alsSD in B. subtilis 168

Glucose

19.8

0.396

[46]

BS-PAR

Moderating expression of the transcriptional regulator AlsR in B. subtilis 168

Glucose

41.5

0.346

[23]

B. subtilis IPE5-4-UD-4

By compound mutagenesis

Pretreated corncob

22.76

0.46

[47]

B. subtilis BMN

Inactivation of AR, moderate expression of NOX

Glucose

56.70

NA

[13]

B. subtilis

BSK814A4

Deletion of araR, bdhA, and acoA; and insertion of a native xyl operon into the genome-reduced B. subtilis BSK814, which is derived from B. subtilis 168

Xylose

23.3

0.466

[4]

BSMAY-4-PsrfA

Optimization of sump cell and intracellular coenzyme balance, combined with blocking of competing pathways and enhancement of alsSD

Pretreated bagasse

Lignocellulose

64.26

0.437

This study