Strains | l-Ornithine titer (g/L) | Yield (g/g) | Carbon source | Cultivation | Strategies | References |
---|---|---|---|---|---|---|
C. glutamicum MTL13 | 54.56 | 0.47 | Mannitol | Fed-batch | Deletion of mtlR; overexpression of mtlD and pfkB | [21] |
C. glutamicum KBJ11 | 88.26 | 0.414 | Glucose | Fed-batch | Deletion of argF, argR, and ncgl2228; co-overexpression of CsgapC and BsrocG | [14] |
C. glutamicum XAB03 | 41.5 | ND | Xylose and glucose | Shake flask | Heterologous expression of xylAB (X. campestris) Overexpression of pepc and araE | [40] |
C. glutamicum SO26 | 43.6 | 0.34 | Glucose | Fed-batch | Deletion of argF, ncgl1221, argR, putP, mscCG2, and iolR; attenuation of odhA, proB, ncgl2228, pta, cat, and pgi; overexpression of lysE, gdh, cg3035, pfkA, tkt, argCJBD, glt, and gdh2 | [13] |
C. glutamicum SO29 | 18.6 | 0.40 | Xylose | Shake flask | Heterologous expression of xylAB operon (X. campestris) | [13] |
C. crenatum Cc-QF-4 | 12.6 ± 0.65; 40.4 | 0.126 ± 0.011; ND | Glucose | Shake flask; bioreactor | Deletion of proB and argF; co-expression of exogenous Ec argA and Sm argE | [6] |
C. glutamicum 1006∆argR-argJ | 31.6 | 0.396 | Glucose | Shake flask | Deletion of argR; overexpression of argJ | [41] |
C. glutamicum YW06 (pSY223) | 51.5 | 0.240 | Glucose | Fed-batch | Deletion of proB, argR, and argF; overexpression of argCJBD, pgi, zwf, and tkt; | [10] |
S. cerevisiae M1dM2qM3e | 5.1 | ND | Glucose | Fed-batch | Modular pathway rewiring | [42] |
C. glutamicum ∆APE6937R42(pEC-SacC) | 22.0; 27.0 | ND | Sucrose; molasses | Batch | Overexpression of sacC (M. succiniciproducens) | [16] |
C. glutamicum SJC8260 | 12.48 | ND | Glucose | Shake flask | Overexpression of ncgl0462 and mutant argCJBD | [43] |
C. glutamicum APE6937R42 | 24.1 | 0.298 | Glucose | Bioreactor | Deletion of argF, argR, and proB; adaptive evolution in presence of l-ornithine | [4] |
C. glutamicum SJC8399 | 13.16 | ND | Glucose | Shake flask | Inactivation of gntK | [44] |