Fig. 2

Peroxisome and cytoplasm dual compartmentalization of mevalonate synthetic pathway to improve mevalonate production from lipids. A The mevalonate synthetic pathway was dual compartmentalized in both peroxisomes and the cytoplasm. B The localization of the ePTS1 signal peptide in Y. lipolytica. The ePTS1 signal peptide was fused to the C-terminus of hrGFP. The peroxisome protein POT1 was fused with mCherry as a peroxisome localization marker. C The mevalonate production of different strains using oleic acid and glucose. Data represent the mean ± SD of three biological replicates