Fig. 3
From: Characterization of an Entner–Doudoroff pathway-activated Escherichia coli
The effect of the redistribution of metabolic flux between PPP and EDP on cell growth and the NADPH/NADP ratio. a Schematic diagrams for possible glycolytic flux redistribution in ALE-1 pRFP (active EDP), ALE-1 pGnd (active both PPP and EDP), and ALE-1 pGnd-GntR (more active PPP and weaker EDP). The effect of gradually increasing glycolytic flux redistribution from the EDP to the PPP in the evolved ALE-1 strain on (d) cell growth and e [NADPH]/[NADP+] ratio. Error bars indicate standard deviations of growth measurements for three independant biological replicates. An asterisk (*) indicates a significant difference compared to the ALE-1 pRFP (p < 0.05)