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Table 4 Metabolite analysis of the K. pneumoniae GEM167ΔadhEΔbudA/pBR-1,2PDO strain after fed-batch cultivation for 48 h

From: Production of 1,2-propanediol from glycerol in Klebsiella pneumoniae GEM167 with flux enhancement of the oxidative pathway

Strain

Maximum metabolite concentration

Glycerol consumption (g/L)

Cell growth (OD 600 nm)

1,2-PDO (mg/L)

2,3-BDO (g/L)

Lactic acid (g/L)

Acetic acid (g/L)

Succinate (g/L)

Ethanol (g/L)

1,3-PDO (g/L)

GEM167ΔadhE/pBR-1,2PDO

158.0 ± 1.1

18.4 ± 0.7

731.0 ± 24.7

51.9 ± 2.3

16.5 ± 1.4

14.1 ± 0.6

1.2 ± 0.2

1.7 ± 0.1

0.2 ± 0.1

GEM167ΔadhEΔbudA/pBR-1,2PDO

54.7 ± 1.4

15.8 ± 0.7

493.8 ± 17.9

1.9 ± 1.3

6.2 ± 0.9

14.3 ± 0.4

0.3 ± 0.1

1.6 ± 0.1

0.4 ± 0.1