Figure 7
From: Addition of a carbohydrate-binding module enhances cellulase penetration into cellulose substrates
Proposed model for chimeric cellulase degradation of amorphous cellulose substrates. Wild-type cellulases (without CBM) are limited to surface degradation, while physical linkage to CBM permits penetration into the bulk of the substrate. Hydrolysis within the bulk creates sites for water coupling and enhanced enzymatic access to additional substrate, resulting in swelling.