Strategies for improved isopropanol–butanol production by a Clostridium strain from glucose and hemicellulose through consolidated bioprocessing

Table 3 Comparison of direct biobutanol production from cellulose and hemicellulose by different Clostridium sp. strains

Organism	Genotype	Substrate	Butanol (g/L)	Total solvents (g/L)	References
C. cellulolyticum	Genetically modified^a	Crystalline cellulose	0.66	0.66	[23]
C. thermocellum	Genetically modified^b	Crystalline cellulose	5.4	5.4	[24]
C. cellulovorans	Genetically modified^c	Crystalline cellulose	1.42	3.02	[25]
C. pasteurianum GL11	Wild type	Birchwood xylan	1.48	6.60	[26]
Clostridium sp. strain NJP7	Wild type	Birchwood xylan	2.06	5.84	This study

^aStrain with introduction of kivd, 2-ketoacid decarboxylase; yqhD alcohol dehydrogenase/aldehyde reductase, alsS acetolactate synthase, ilvC acetohydroxyacid isomeroreductase, ilvD dihydroxy-acid dehydrogenase
^bStrain with introduction of kivd, 2-ketoacid decarboxylase, ilvBN acetohydroxy acid synthase (AHAS), ilvC acetohydroxyacid isomeroreductase, ilvD dihydroxy-acid dehydrogenase
^cStrain with introduction of aldehyde/alcohol dehydrogenase (adhE2)

ISSN: 2731-3654