Fig. 7

Secreted protein titres in submerged cultivation. Total secreted protein (mg) was determined from culture supernatants using a Bradford assay, which was normalized to fungal biomass (g dry weight). Error bars report standard deviation from triplicate biological replicate. p values < 0.05 are depicted with an asterisk. Asterisks indicate where protein titres of mutant isolate significantly deviates from MA70.15 control at the respective Dox concentration (t-test)