Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in Aspergillus niger

Table 1 Strains generated in this study

Gene name^a	Gene	Strain name (this study)	Predicted functional category^b	Function or experimental characterization as described in yeast and filamentous fungi^b	Evidence of morphogene function
crzA	An01g13700	TK26.2	Transcription factor	Transcription factor which activates expression of stress response genes; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation	[29]
amgA	An12g10750	TK28.5	Transcription factor	Gene deletion impacts shmoo formation in Schizosaccharomyces pombe	[30]
rscI	An11g02670	TK38.5	Component of the RSC chromatin remodelling complex	Rsc9 is involved in both repression and activation of mRNAs regulated by target of rapamycin (TOR)	[31]
strA	An16g01520	TK39.1	WD-repeat protein that regulates sexual development	Regulates sexual development and localizes to endoplasmic reticulum in Aspergillus nidulans	[32]
cihA	An07g01060	TK51.1	Has domains with predicted role in cell wall macromolecule catabolic process	Possible cell wall associated protein	[33]
dlpA	An08g10160	TK53.1	Dehydrin-like protein	Deletion mutant impacts conidiation in A. nidulans	[34]

^aNaming follows the nomenclature for filamentous fungi
^bPredicted functional categories were derived from the Ensemble or FungiDB databases

ISSN: 2731-3654