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Table 2 Performances of different documented strains for 4-HBC production

From: Unravelling and engineering an operon involved in the side-chain degradation of sterols in Mycolicibacterium neoaurum for the production of steroid synthons

Strains

Substrates (g/L)

Titer (g/L)

Refs.

Mycobacterium sp. NRRLB-11389

Cholesterol (10)

0.44

[54]

M. neoaurum DSM 1381ΔkstD1

Phytosterols (20)

14.18

[55]

M. neoaurum XIIΔhsd4AΔkstD123

Phytosterols (40)

5.24–5.75

[18]

M. neoaurum WIIIΔmmpL3-cyp125-choM1-fadA5

Phytosterols (20)

7.59

[56]

M. neoaurum WIIIΔmmpL3-pbpB

Phytosterols (20)

6.66

[57]

M. neoaurum WIII-egt&msh&cat

Phytosterols (20)

12.5

[9]

M. neoaurum WIIIΔkasB

Phytosterols (20)

7.8

[10]

M. neoaurum mJTU8

Phytosterols (20)

7.41

[40]

M. neoaurum WIIIΔCSNDΔfadA5-IV

Phytosterols (30)

20.7

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