Fig. 6

Mass fractions of different metabolites calculated from the Raman signal of flow cell 2 (see Additional file 1: Fig. S7) behind the adsorption column. Depicted are mass fractions of the analysed Raman-active substances over time and the different phases of the product separation cycle according to Fig. 3. Start and end points of different phases in the experiment were adjusted according to the measured Raman signals. The displayed product separation cycle is the second cycle from the experiment displayed in Fig. 7 (87.4–99.5 h). The column was filled with 47 mL of Blücher 100562 activated carbon