Fig. 7

Proposed model for enhancing the lignocellulases secretion in T. guizhouense under heat stress by deleting the gene Tgparp. ER stress and gene Tgparp expression could be activated by heat stress and nutrition stress. Deletion of Tgparp maintains energy homeostasis, allocating more ATP to the ER for protein folding or refolding. This prevents excessive protein aggregation in the ER, thereby promoting the lignocellulases secretion of T. guizhouense under heat stress