Xylose reductase from Pichia stipitis with altered coenzyme preference improves ethanolic xylose fermentation by recombinant Saccharomyces cerevisiae

Table 6 Strain comparison

Strain	Relevant genotype	Dilution rate	Xylose consumption rate	Ethanol yield	Xylitol yield	Reference
TMB3001	XYL1, XYL2, XKS1	0.06	0.12	0.37	0.52	[13]
TMB3260	(2 × XYL1), XYL2, XKS1	0.06	0.19	0.36	0.58	[13]
TMB3270	XYL1(K270M), XYL2, XKS1	0.06	0.05	0.40	0.31	[13]
TMB3271	(2 × XYL1(K270M)), XYL2, XKS1	0.06	0.16	0.40	0.44	[13]
TMB3400	XYL1, XYL2, XKS1, Mutated TMB3399	0.06	0.22	0.35	0.19	[1]
C1	XYL1, XYL2, XKS1, Evolved TMB3001	0.05	0.31	0.27^a	0.35^a	[38]
Y-PsNative	XYL1, XYL2, XKS1, ΔGRE3, overexpressed non-oxidative PPP	0.06	0.19	0.37	0.30	This work
Y-PsK270R	XYL1(K270R), XYL2, XKS1, ΔGRE3, overexpressed non-oxidative PPP	0.06	0.22	0.39	0.12	This work

Xylose consumption rate (g (g biomass)^-1 h^-1), ethanol yield (g (g consumed sugars)^-1) and xylitol yield (g (g consumed xylose)^-1) in anaerobic continuous fermentation with recombinant S. cerevisiae strains, 10 g l^-1 glucose and 10 g l^-1 xylose.
^a Recalculated

ISSN: 2731-3654