Table 2 pK a values of compounds and relative toxicities for glucose and xylose were calculated by dividing the mean of inhibitor concentrations at IC 25 , IC 50 , IC 75 and IC 100 when grown in glucose divided by the mean inhibitor concentration at respective IC when grown in xylose
From: Inhibition of growth of Zymomonas mobilis by model compounds found in lignocellulosic hydrolysates
Compound | pKa | Average ratio of IC in RMG/IC in RMX |
|---|---|---|
Organic acids | Â | Â |
Levulinc acid | 4.59 | 4.5 +/- 0.5 |
Benzoic acid | 4.18 | 4.1 +/- 1.3 |
Acetic acid | 4.76 | 3.7 +/- 0.4 |
Formic acid | 3.75 | 3.2 +/- 0.8 |
Caproic (Hexanoic) acid | 4.85 | 2.2 +/- 0.4 |
Lactic acid | 3.86 | 1.9 +/- 0.4 |
2-Furoic acid | 3.16 | 1.9 +/- 0.4 |
Vanillic acid | 4.31, 8.81 | 1.4 +/- 0.1 |
Ferulic acid | 4.56, 8.65 | 1.4 +/- 0.1 |
4-Hydroxycinnamic acid | 4.63, 9.58 | 1.3 +/- 0.2 |
4-Hydroxybenzoic acid | 4.48, 9.32 | 1.1 +/- 0.06 |
Itaconic acid | 3.85, 5.45 | 0.9 +/- 0.1 |
Succinic acid | 4.16, 5.61 | 1.0 +/- 0.2 |
Oxalic acid | 1.27, 4.27 | 0.9 +/- 0.04 |
Inorganic acids | Â | Â |
Hydrochloric acid | Â | 0.8 +/- 0.2 |
Sulfuric acid | Â | 0.7 +/- 0.1 |
Phosphoric acid | Â | 0.6 +/- 0.1 |
Nitric acid | Â | 1.1 +/- 0.1 |
Aldehydes | Â | Â |
5-Hydroxymethylfurfural (HMF) | -0.37 | 1.0 +/- 0.1 |
Furfural | 0.41 | 0.8 +/- 0.1 |
Syringaldehyde | 0.99 | 0.9 +/- 0.1 |
Vanillin | 1.21 | 1.5 +/- 0.4 |
4-Hydroxybenzaldehyde | 1.35 | 1.6 +/- 0.1 |
Alcohols | Â | Â |
Furfuryl alcohol | 0.28 | 1.0 +/- 0.1 |
Ethanol | -0.24 | 1.0 +/- 0.1 |