Figure 2

Phylogeny of C. clariflavum cohesins. A set of 47 C. clariflavum (Cc), 41 A. cellulolyticus (Ac), and 18 C. thermocellum (Ct) cohesin-like modules, derived from deduced amino-acid sequences (supporting Additional file 1: Figure S1), was aligned using the CLUSTALW2 program at the EBI website [35], which then served to reconstruct an unrooted phylogenetic tree by the MEGA5.10 software [36], using the neighbor-joining method with 500 bootstrap replicates. Numerical values above the nodes indicate bootstrap percentiles. The cohesin-like modules distribute into two major classes: type I (yellow) and type II (green). Among the type I cohesin-like modules one subgroup is separated from the majority of the modules (pink).