Skip to main content

Advertisement

Table 3 Identified reactions that contribute significantly to the predicted maximum cytochrome c and flavin production rates

From: Theoretical exploration of optimal metabolic flux distributions for extracellular electron transfer by Shewanella oneidensisMR-1

Reaction ID Flux Enzyme EC Number Reaction Subsystems
Min Max
CYOO2 75.12 81.68 Cytochrome-c oxidase (2 protons translocated) 1.9.3.1 (2) focytcc [c] + (4) h [c] + (0.5) o2 [c] -->(2) ficytcc [c] + (2) h [e] + h2o [c] Energy metabolism
SO3De 0 -6.559 Sulfite dehydrogenase 1.8.2.1 (2) ficytcc [c] + h2o [e] + so3 [e] -->(2) focytcc [c] + (2) h [e] + so4 [e] Energy metabolism
RBFK -0.2504 -0.2504 Riboflavin kinase 2.7.1.26 [c] : atp + ribflv -->adp + fmn + h Cofactor and prosthetic group biosynthesis
RBFSb 0.5008 0.5008 Riboflavin synthase 2.5.1.9 [c] : (2) dmlz -->4r5au + ribflv Cofactor and prosthetic group biosynthesis
FMNRx 0.2504 0.2504 FMN reductase (NADH dependent) 1.5.1.29 [c] : fmn + h + nadh -->fmnRD + nad Cofactor and prosthetic group biosynthesis
  1. (Note: Whereas the flux values for CYOO2 and SO3De are calculated by multiplying the reaction flux (not shown) and the stoichiometry coefficient of the cytochrome c, the flux values for RBFK, RBFSb and FMNRx are calculated by multiplying the reaction flux (not shown) and the stoichiometry coefficient of the riboflavin or FMN.)
  2. The flux ranges were calculated from the FATMIN algorithm.