Theoretical exploration of optimal metabolic flux distributions for extracellular electron transfer by Shewanella oneidensisMR-1

Table 3 Identified reactions that contribute significantly to the predicted maximum cytochrome c and flavin production rates

Reaction ID	Flux		Enzyme	EC Number	Reaction	Subsystems
Reaction ID	Min	Max	Enzyme	EC Number	Reaction	Subsystems
CYOO2	75.12	81.68	Cytochrome-c oxidase (2 protons translocated)	1.9.3.1	(2) focytcc [c] + (4) h [c] + (0.5) o2 [c] -->(2) ficytcc [c] + (2) h [e] + h2o [c]	Energy metabolism
SO3De	0	-6.559	Sulfite dehydrogenase	1.8.2.1	(2) ficytcc [c] + h2o [e] + so3 [e] -->(2) focytcc [c] + (2) h [e] + so4 [e]	Energy metabolism
RBFK	-0.2504	-0.2504	Riboflavin kinase	2.7.1.26	[c] : atp + ribflv -->adp + fmn + h	Cofactor and prosthetic group biosynthesis
RBFSb	0.5008	0.5008	Riboflavin synthase	2.5.1.9	[c] : (2) dmlz -->4r5au + ribflv	Cofactor and prosthetic group biosynthesis
FMNRx	0.2504	0.2504	FMN reductase (NADH dependent)	1.5.1.29	[c] : fmn + h + nadh -->fmnRD + nad	Cofactor and prosthetic group biosynthesis

(Note: Whereas the flux values for CYOO2 and SO3De are calculated by multiplying the reaction flux (not shown) and the stoichiometry coefficient of the cytochrome c, the flux values for RBFK, RBFSb and FMNRx are calculated by multiplying the reaction flux (not shown) and the stoichiometry coefficient of the riboflavin or FMN.)
The flux ranges were calculated from the FATMIN algorithm.

ISSN: 2731-3654