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Table 2 Reducing equivalent dependence analysis of various acids, solvents, and hydrogen

From: Capturing the response of Clostridium acetobutylicumto chemical stressors using a regulated genome-scale metabolic model

 

Glucose

Glycerol

Metabolites

With redox constraint

No redox constraint

 

Carbon source

10.00

10.00

20.00

Acetate

23.74

23.74

25.16

Butyrate

0.96

8.59

10.79

Ethanol

12.17

17.68

16.32

Acetone

7.34

17.01

17.04

Butanol

5.75

9.65

12.65

Hydrogen

31.18

35.85

61.73

  1. Comparisons made between glucose with and without constraints on production of reducing equivalents and glycerol. Equivalent carbon flux values were chosen for both glucose and glycerol. All values except for carbon source uptake represent production fluxes with units of mmol gDW−1 h−1. Increasing availability of reducing equivalents led to increased product formation for all cases except acetate.