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Table 3 Inventory of the mutations affecting genes regulated during induction by lactose

From: Kinetic transcriptome analysis reveals an essentially intact induction system in a cellulase hyper-producer Trichoderma reesei strain

Transcript ID Cluster Annotation Strain Mutation Position Reference
NG 14 and RUT C30 strains
1751 1 Putative FAD monooxygenase RUT C30 SNV Promoter [21]
54511 5 Putative POZ domain protein RUT C30 SNV Promoter [21]
56077 5 Putative transcription factor RUT C30 SNV Promoter [21]
77513 5 Putative fungal C6 transcription factor RUT C30 SNV Exon [21]
121087 Not clustered Putative 4Fe-4S ferredoxin domain protein NG 14 & RUT C30 SNV Promoter [21]
Other cellulase improved strains
54736 1 Putative ATP-dependent RNA helicase DED1 KDG-12 PC-3-7 SNV Promoter [23]
58427 1 Putative ATP-dependent RNA helicase DBP2 PC-3-7 SNV Exon [24]
71380 1 Putative 3-hydroxy-3-methylglutaryl-coenzyme A reductase PC-3-7 SNV Exon [24]
78836 1 Putative mitochondrial phosphate carrier PC-3-7 SNV Exon [24]
82512 1 Putative 26S proteasome transcription factor RPN4 PC-3-7 SNV Promoter [24]
122036 1 Putative 40S ribosomal protein S2 RPS2 QM9414 KDG-12 PC-3-7 InDel & SNV Promoter & Terminator [25]
63882 4 Putative mitochondrial 3-hydroxyisobutyryl-CoA hydrolase PC-3-7 SNV Terminator [24]
124031 4 Putative 20S proteasome alpha 3 subunit PRE9 PC-3-7 SNV Promoter [24]
6108 5 Putative SAM binding domain protein QM9414 KDG-12 PC-3-7 InDel Intron Unpublished data
112390 5 Putative WD40 repeat domain protein QM9414 KDG-12 PC-3-7 InDel Terminator Unpublished data
120688 5 Putative protein of unknown function QM9414 KDG-12 PC-3-7 InDel Exon Unpublished data
110853 6 Putative glutathione S-transferase PC-3-7 SNV Terminator [24]
77481 8 Putative D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase PC-3-7 SNV Exon [24]
120749 8 Glycoside hydrolase family 1 BGL2 KDG-12 PC-3-7 SNV Exon [23]
  1. We differentiate common mutations to RUT C30 and NG 14 strains from the mutations specific for RUT C30 strain. Mutations in regulated genes described in other cellulase improved strains are shown. Mutations are described as single nucleotide variation (SNV) and deletions or insertions (InDel). Affected gene region is also provided.