Complex and extensive post-transcriptional regulation revealed by integrative proteomic and transcriptomic analysis of metabolite stress response in Clostridium acetobutylicum

Table 1 Differential expression analysis of proteomic data

A. Butanol stress
	Low BuOH		Med BuOH		High BuOH
Total proteins used for DE analysis	243		280		222
	Up	Down	Up	Down	Up	Down
DE proteins (FDR 5 %)	23	40	20	63	53	63
DE proteins (FDR 5 %, fold change ≥2.0)	15	33	20	56	34	41
Proteins expressed only under stress	37		59		25
Proteins expressed only under non-stress control	44
B. Butyrate stress
	Low BA		Med BA		High BA
Total proteins used for DE analysis	337		344		357
	Up	Down	Up	Down	Up	Down
DE proteins (FDR 5 %)	54	19	60	41	68	32
DE proteins (FDR 5 %, fold change ≥2.0)	38	17	38	26	36	22
Proteins expressed only under stress	43		70		61
Proteins expressed only under non-stress control	67

ISSN: 2731-3654