Fig. 1
From: Bioenergetic constraints for conversion of syngas to biofuels in acetogenic bacteria
Enzymology of the Wood–Ljungdahl pathway. One CO2 is reduced to a THF-bound methyl group, a second CO2 is reduced to an enzyme-bound CO group. The methyl and the CO group are condensed by the CODH/ACS and further converted to acetate. [H] reducing equivalent; THF tetrahydrofolate; CoFeS corrinoid–iron-sulfur protein; CODH/ACS carbon monoxide dehydrogenase/acetyl-CoA synthase