Fig. 1
From: Engineering Bacillus licheniformis for the production of meso-2,3-butanediol
Metabolic pathway of 2,3-butanediol synthesis in B. licheniformis WX-02 (modified based on [9, 24, 41, 44]). ALS α-acetolactate synthase, ALDC α-acetolactate decarboxylase, BDH 2,3-butanediol dehydrogenase, AAS acetylacetoin synthase, AAR acetylacetoin reductase, DR diacetyl reductase, AoDH ES acetoin dehydrogenase enzyme system. The solid arrows indicate the reactions; the dashed arrows indicate the regulatory events; the dashed square marks the hypothetical 2,3-butandiol cycle; the crosses indicate the disruption of the target pathways in this work