Fig. 2

Transcriptional analyses reveal how Aspergillus nidulans adapts to growth on SEB. a Significant transcriptional modulation of genes encoding for transcription factors involved in alternative carbon usage, starvation responses, and morphological adaptations post transfer to SEB. b Transcriptional induction of an array of CAZymes post transfer to SEB, in particular those from the GH families which target hemicellulose GH2, GH3, GH10, GH11, GH43, GH62) or lignin (GH61 now reclassified as AA9). c Transcriptional induction of numerous putative and characterised sugar transporter encoding genes post transfer to SEB. d RT-qPCR analysis of 17 putative sugar transporter encoding genes validates RNA-seq data. A heatmap of the RT-qPCR analysis showing the expression of 17 genes during growth on 1 % fructose, 0.1 % xylose, 1 % xylose, and 0.5 % SEB. The majority of genes showed higher expression levels at low xylose concentrations implying that they encoded putative high affinity transporters