Robust succinic acid production from crude glycerol using engineered Yarrowia lipolytica

Table 2 Comparison of SA production by fed-batch fermentation strategy

Microorganism	Carbon source	SA titer (g L⁻¹)	SA yield (g g⁻¹)	SA productivity (g L⁻¹ h⁻¹)	References
A. succinogenes GXAS137	Sugarcane molasses	64.7	0.81	1.3	[32]
C. glutamicum CGMCC1006-ΔldhA	Sugarcane molasses	35.1	0.37	0.65	[34]
E. coli BA305	Sugarcane bagasse	39.3	N/A	0.33	[35]
E. coli KJ122	Cassava pulp	98.6	0.72	1.03	[36]
A. succinogenes ATCC 55618	Rapeseed meal	23.4	N/A	0.33	[37]
A. succinogenes CGMCC1593	Wheat straw	53.2	N/A	1.21	[38]
A. succiniciproducens	Whey	34.7	0.91	1.02	[39]
C. glutamicum ΔldhA-pCRA717	Glucose	146	0.92	3.17	[41]
A. succinogenes ATCC 55618	Glycerol	49.6	0.87	2.31	[25]
E. coli E2-Δsdh-ppc-sucAB	Glycerol	43.2	N/A	0.77	[40]
Y. lipolytica H222-AZ2	Glycerol	25	0.26	0.15	[5]
Y. lipolytica PGC01003	Crude glycerol	160.2	0.4	0.4	This study

ISSN: 2731-3654