Fig. 6

Production comparisons of various isoprenoids from engineered cyanobacteria. Specific production over 48 h culture (mg/L/OD₇₃₀) of amorpha-4,11-diene and squalene (this work in black bar) were compared with the previous results (in gray bar) as the following: (Group I: the proof of concept; bisabolene from Synechococcus sp. PCC 7002 [27], squalene from Synechocystis sp. PCC 6803 [29], limonene from Synechococcus sp. PCC 7002 [27]) (Group II: Pathway optimization; β-phellandrene from Synechocystis sp. PCC 6803 [28], carotenoid from Synechocystis sp. PCC 6803 [30], isoprene from Synechocystis sp. PCC 6803 [26]), and (Group III: Protein fusion with TPS and pathway optimization combined; β-phellandrene from Synechocystis sp. PCC 6803 [55, 57], isoprene from Synechocystis sp. PCC 6803 [56]). The number on the bar indicates specific production over a 48 h culture. The detailed information is described in “Conclusion” and in the Additional file 1: Table S1. MVA Mevalonate