Fig. 7
Overall impact of ethanol stress on C. thermocellum metabolism. a Affected pathway fluxes and metabolite concentrations under ethanol stress condition. The numbers represent the flux values (mol/mol cellobiose) normalized to cellobiose uptake (except for those in brackets represent concentration change) for the wild-type (gray color) to ammonia-limited (green or red color representing up- or downregulation, respectively) conditions. All fluxes were normalized to cellobiose uptake. b Comparison of model-predicted cytosolic concentration changes with the experimentally measured values