Fig. 10

Separation superstructure for intracellular (IN) soluble (SOL) liquid (LQD) volatile (VOL) specialty (SPC) product. The three stages are distinguished based on colors: (I) Cell and product isolation: red; (II) Product concentration: green; and (III) Product purification and refinement: blue. The technologies involved are flocculation (Flc,1,2), sedimentation (Sdm,1,2), centrifugation (Cnt,1,2), filtration (Ftt,1,2), enzyme lysis (Ely), bead milling (Bml), membrane processes (microfiltration (MF) and ultrafiltration (UF)), distillation (Dst,1,2), aqueous two-phase extraction (Atpe), extraction (Ext), chromatography (Chr), pervaporation (Pvp), and bleaching (Blc). Options for bypassing (Byp,1,2) a stage or some tasks are also included