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Table 5 Parameters selected for analysis in study 1

From: Synthesis and analysis of separation networks for the recovery of intracellular chemicals generated from microbial-based conversions

Separation stage and task Parameter Base case (nominal) Range References
Stage I: input parameter Biomass titer in input process stream 5 g/L (0.1–200) [45, 118,119,120]
Stage I: task—cell harvesting Cell separation efficiency for centrifugation (Cnt,1) 80% (70–95) [64, 121]
Cell retention factor for filtration (Ftt,1) 80% (70–95) [85]
Stage I: task—cell disruption % Release for acid hydrolysis (Ahy) 85% (80–98) [122]
% Release for bead mill (Bml) 85% (80–98) [123]
% Release for enzyme lysis (Ely) 90% (85–98) [124]
Stage I: task—phase isolation Amount of agent required for differential digestion (Ddg) 0.4 kg/kg other cell components (0.05–3) [109]
Amount of solvent required for solubilization (Slb) 0.4 kg/kg product (0.05–3) [107]