Table 1 Current advance in high-titer ABE production based on two-stage ISPR processes
Processes | Substrate | Strains | First-stage separation | Second-stage separation | References | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Butanol in bioreactor (g/L) | Butanol (g/L) | ABE (g/L) | Butanol (g/L) | ABE (g/L) | Ethanol recovery (%) | Acetone recovery (%) | Butanol recovery (%) | ||||
One-stage separation | |||||||||||
Gas stripping | Glucose | C. acetobutylicum ABE 1401 | 14.3 | 115 | 180 | – | – | – | – | – | [17] |
Salting-out | Glucose | – | – | NG | NG | – | – | ~ 40a | ~ 72a | ~ 100a | [26] |
Two-stage separation | |||||||||||
Gas stripping–pervaporation | Glucose | C. acetobutylicum ABE 1401 | 10–12 | 108.3 | 177.6 | 482.55 | 706.68 | 82.8 | 99.5 | 98.8 | [12] |
Glucose | C. acetobutylicumJB200 | 16.2 | 155.6 | 199.9 | 441.7 | 593.2 | 87.5 | 81.4 | 92.2 | [9] | |
Two-stage gas stripping | Glucose | C. acetobutylicumJB200 | 19.2 | 175.6 | 227.0 | 420.3 | 532.3 | 99.1 | 78.9 | 85.4 | [8] |
Two-stage pervaporation | Glucose | C. acetobutylicum ABE 1401 | 10–12 | 199.1 | 346.5 | 451.98 | 782.5 | ~ 67 | ~ 100 | 99.3 | [33] |
Extraction-gas stripping | Glucose | C. acetobutylicum ATCC 824 | NG | 29–32 | 37–42 | 200–250 | 360–460 | NG | NG | 88 | [32] |
Fraction-salting-out | – | – | – | ~ 260 | ~ 400 | NG | NG | 98.2 | 100 | 100 | [25] |
Gas stripping–salting-out | SSB | C. acetobutylicum ABE 1201 | 8.6–9.4 | 95.1 | 143.6 | 520.3 | 747.59 | 89.31 | 99.12 | ~ 100 | This work |