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Table 1 Current advance in high-titer ABE production based on two-stage ISPR processes

From: Integrated in situ gas stripping–salting-out process for high-titer acetone–butanol–ethanol production from sweet sorghum bagasse

Processes Substrate Strains First-stage separation Second-stage separation References
Butanol in bioreactor (g/L) Butanol (g/L) ABE (g/L) Butanol (g/L) ABE (g/L) Ethanol recovery (%) Acetone recovery (%) Butanol recovery (%)
One-stage separation
 Gas stripping Glucose C. acetobutylicum ABE 1401 14.3 115 180 [17]
 Salting-out Glucose NG NG ~ 40a ~ 72a ~ 100a [26]
Two-stage separation
 Gas stripping–pervaporation Glucose C. acetobutylicum ABE 1401 10–12 108.3 177.6 482.55 706.68 82.8 99.5 98.8 [12]
  Glucose C. acetobutylicumJB200 16.2 155.6 199.9 441.7 593.2 87.5 81.4 92.2 [9]
 Two-stage gas stripping Glucose C. acetobutylicumJB200 19.2 175.6 227.0 420.3 532.3 99.1 78.9 85.4 [8]
 Two-stage pervaporation Glucose C. acetobutylicum ABE 1401 10–12 199.1 346.5 451.98 782.5 ~ 67 ~ 100 99.3 [33]
 Extraction-gas stripping Glucose C. acetobutylicum ATCC 824 NG 29–32 37–42 200–250 360–460 NG NG 88 [32]
 Fraction-salting-out ~ 260 ~ 400 NG NG 98.2 100 100 [25]
 Gas stripping–salting-out SSB C. acetobutylicum ABE 1201 8.6–9.4 95.1 143.6 520.3 747.59 89.31 99.12 ~ 100 This work
  1. NG not given
  2. a The recovery of organic solvent from the first-stage salting-out