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Table 2 Mutations selected in this study to understand high PA production in WGS7

From: Linking genotype and phenotype in an economically viable propionic acid biosynthesis process

Genome coordinatea

Type

Reference

Alternate

Gene function

Origin

Remark

1,917,729

SNP

G

A

Multiple sugar ABC transporter, substrate-binding protein

ATCC4965 or ATCC4875

Promoter

1,487,806

SNP

C

T

Cytochrome c-type biogenesis

E

R134Q

2,293,187

SNP

C

T

Amino acid ABC transporter

E

Silent

  1. SNP single nucleotide polymorphism, E elusive
  2. aGenome coordinate in P. acidipropionici ATCC 55737. ATCC4965 P. acidipropionici ATCC 4875; ATCC4875 P. acidipropionici ATCC 4965. Silent: no change in amino acid
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Biotechnology for Biofuels and Bioproducts

ISSN: 2731-3654

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