Fig. 3
Numbers of the unique and shared differentially expressed proteins of the six inhibitor-treated groups. a The numbers of unique and shared up-regulated proteins in the presence of different inhibitors, and b the numbers of unique and shared down-regulated proteins in the presence of different inhibitors. These protein numbers are shown in an UpSet diagram, which allows for a clearer plotting of large data sets compared to the Venn diagram. Dark circles connected with a line indicate that the proteins are only differentially expressed in the corresponding groups labeled with dark circles, but not in the other groups labeled with gray circles. For example, â‘ denotes the proteins are only differentially expressed in phenol-treated group, while not differentially expressed in the other groups, that is, these proteins are unique in phenol-treated group; â‘¡ denotes the proteins are differentially expressed in all the groups, that is, these proteins are shared by all the groups; â‘¢ denotes the proteins are only differentially expressed in formic acid, furfural, 5-HMF, and combined inhibitors treated groups, while not differentially expressed in acetic acid and phenol-treated groups. Combined inhibitors means a combination of formic acid, acetic acid, furfural, 5-HMF, and phenol