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Table 1 Pathway analysis of differentially expressed genes (DEGs) in kpG_48-vs-kpC_48

From: Improved xylose tolerance and 2,3-butanediol production of Klebsiella pneumoniae by directed evolution of rpoD and the mechanisms revealed by transcriptomics

Pathway

DEGs numbers

All-unigene numbers

P value

Q value

Pathway ID

Purine metabolism

23 (5.08%)

96 (24.73%)

0.00

0.31

ko00230

Lysine biosynthesis

8 (1.77%)

23 (34.78%)

0.01

0.31

ko00300

Lipopolysaccharide biosynthesis

7 (1.55%)

19 (36.84%)

0.01

0.31

ko00540

d-Alanine metabolism

2 (0.44%)

2 (100%)

0.02

0.46

ko00473

Flagellar assembly

5 (1.1%)

13 (38.46%)

0.02

0.46

ko02040

Pyrimidine metabolism

11 (2.43%)

46 (23.91%)

0.03

0.55

ko00240

Ubiquinone and other terpenoid-quinone biosynthesis

10 (0.95%)

12 (83.33%)

0.00

0.02

ko00130

Two-component system

78 (7.4%)

193 (40.41%)

0.00

0.05

ko02020

Pantothenate and CoA biosynthesis

16 (0.87%)

17 (94.12%)

0.00

0.03

ko00770

Fatty acid biosynthesis

10 (1.69%)

29 (34.48%)

0.02

0.86

ko00061

Biosynthesis of secondary metabolites

55 (17.86%)

463 (35.95%)

0.02

0.20

ko01110

Nicotinate and nicotinamide metabolism

5 (1.62%)

17 (29.41%)

0.01

0.20

ko00760

Phosphatidylinositol signaling system

6 (1.19%)

16 (37.5%)

0.02

0.26

ko04070

Oxidative phosphorylation

48 (9.52%)

104 (47.12%)

0.00

0.00

ko00190

Phosphotransferase system (PTS)

8 (3.96%)

68 (11.76%)

0.05

0.47

ko02060