Fig. 3

Differences in the two binding site architectures of family 4, 17, and 28 CBMs. Illustrated through hydrophobic interactions (dark blue sticks and transparent surface) and hydrogen bonding (red sticks) with the cellopentaose ligand (light green and red sticks). The front view (top left) and side view (top right) of the CfCBM4-1 binding site with bound cellopentaose clearly show the sandwich platform and deep cleft with one-sided hydrogen bonding of the ligand. The front view (bottom left) and side (bottom right) of the CjCBM28 binding site with bound cellopentaose show a twisted surface platform and shallow groove with hydrogen bonding partners available on both sides of ligand. The numbers on the cello-oligomeric ligand represents the binding subsite number