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Table 1 Overview of recent studies on LA production in SSF using different B. coagulans strains

From: Seed culture pre-adaptation of Bacillus coagulans MA-13 improves lactic acid production in simultaneous saccharification and fermentation

Strain Biomass Process Lactic acid References
Raw material Pre-treatment Detoxification Seed culture medium Fermentation set-up Temperature (°C) pH Enzyme load Process time (h) LA avg. vol. productivity (g/(L h)) Yield (g/g)
MA-13 Wheat straw H2SO4-steam explosion SM-0% SSF 55 5.5 10 FPU/gWIS 30 1.11 1.23a/1.24b/0.27c This work
SM-30% 15 1.74 1.02a/1.10b/0.27c
DSM 2314 Birch wood Steam explosion Water washing TSNT SSF 50 5.5 2 mg/gDM 120 0.35 0.79b [28]
CC17 Bagasse Sulfite pulping Water washing GCY Fed-batch SSF 50 5.0–5.5 10 FPUcellulase/gcellulose
120 Uxylanase/ghemicellulose
120 0.92 0.72b/0.60d [25]
LA204 Corn cob NaOH Water washing YEX Fed-batch SSF 50 6.0 30 (FPU/gcellulose) 90 1.37 0.77c [29]
NH3-H2O2 90 1.32 0.74c
72 1.10 0.43c
LA204 Corn stover NaOH Water washing GY or XY Fed-batch SSF 50 6.0 30 (FPU/gstover) 60 1.63 0.68c [26]
IPE22 Wheat straw H2SO4-steam explosion mMRS SSCF 50 5.0 20 FPU/gcellulose 60 0.43 0.46c [27]
DSM 2314 Wheat straw Lime GY Fed-batch SSF 50 6.0 n.r. 55 0.68 0.43c/0.81d [20]
  1. DM dry matter, FPU filter paper unit, n.r. not reported, U unit; WIS water-insoluble solid
  2. SM-0%; SM-30% Seed medium containing 0% and 30% hydrolysate, respectively (see composition in the paragraph “Strain and media”. )
  3. mMRS modified MRS: 10 g/L peptone; 10 g/L beef extract; 5 g/L yeast extract; 2 g/L K2HPO4; 0.2 g/L MgSO4_7H2O; 0.05 g/L MnSO4_4H2O; 10 g/L glucose
  4. GY 10 g/L glucose; 10 g/L yeast extract; 2 g/L (NH4)2HPO4; 3.5 g/L (NH4)2SO4; 10 g/L Bis–Tris; 0.02 g/L MgCl2·6H20 and 0.1 g/L CaCl2·2H20
  5. TSNT 10 g/L tryptone; 5 g/L soytone; 3 g/L NaCl and 1 g/L Tween 80
  6. GCY 20 g/L glucose; 2.5 g/L corn steep powder; 1 g/L yeast extract; 1 g/L NH4Cl; 0.2 g/L MgSO4 and 10 g/L CaCO3
  7. GY (or XY) 50 g/L glucose (or xylose) and 10 g/L yeast extract
  8. YEX 10 g/L xylose and 10 g/L yeast extract
  9. ag of lactic acid/g of consumed glucose
  10. bg of lactic acid/g of glucose released from cellulose
  11. cg of lactic acid/g of total dry matter
  12. dg of lactic acid/g of total sugars released from the biomass