Maximum likelihood tree of the pyranose oxidase (POx) cluster. Coloured circles and numbers mark the positions and counts of characterised enzymes in the tree. Right: Table of properties for the three defined clades of the tree. Listed organisms are sorted according to their appearance in the tree (top to bottom). 1—Takakura and Kuwata ; 2—Artolozaga et al. ; 3—Danneel et al. ; 4—US Patent 6146865, 2000; 5—Maresova et al. ; 6—Daniel et al. ; 7—Vecerek et al. ; 8—Bannwarth et al. ; 9—Pisanelli et al.