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Table 2 Occurrence of the SNPs identified in the causative genes in 1011 natural yeast isolates

From: Polygenic analysis of very high acetic acid tolerance in the yeast Saccharomyces cerevisiae reveals a complex genetic background and several new causative alleles

Gene

Strain

SNP position in ORF/amino acid in gene product

SNF4

 

593

805

807

   

16D

G/S

G/E

G/E

   

MS164

A/N

T/*

A/*

   

1011 genomes

4% G/S

100% G/E

50% G/E

   
 

96% A/N

 0% T/*

50% A/E

   

TRT2

 

28

     

16D

G

     

MS164

T

     

1011 genomes

100% G

     
 

0% T

     

MET4

 

176

335

716

1127

1214

1244

16D

C/A

A/D

T/M

T/I

G/S

A/D

MS164

T/V

G/G

G/R

C/T

A/N

G/G

1011 genomes

6% C/A

90% A/D

62% T/M

53% T/I

66% G/S

66% A/D

 

94% T/V

10% G/G

38% G/R

47% C/T

34% A/N

34% G/G

MSH2

 16D

0 non-synonymous SNPs

     

MS164

     

HAL9

 

249

569

599

817

1067

1190

16D

G/M

A/E

G/S

A/K

G/C

G/S

MS164

A/I

G/G

A/N

G/E

A/Y

A/N

1011 genomes

72% G/M

68% A/E

90% G/S

98% A/K

35% G/C

100% G/S

HAL9

 

 28% A/I

32% G/G

10% A/N

2% G/E

 65% A/Y

0% A/N

 

1276

2048

2240

2315

2647

2735

16D

G/V

G/S

T/L

C/A

T/S

A/E

MS164

A/I

A/N

A/Q

T/V

G/A

T/V

1011 genomes

45% G/V

94% G/S

63% T/L

16% C/A

93% T/S

69% A/E

 

55% A/I

6% A/N

37% A/Q

84% T/V

7% G/A

31% T/V

  

209

289

442

446

602

822-829

 

16D

G/R

G/G

C/H

A/N

G/S

No insertion 

IRA2

MS164

A/Q

T/C

A/N

G/S

A/N

8 bp insertion

 

1011 genomes

88% G/R

99% G/G

49% C/H

38% A/N

14% G/S

100% 

  

12% A/Q 

1% T/C

51% A/N

 62% G/S

86% A/N

0%

RTG1

 

151

334

    

16D

A/S

G/V

    

MS164

G/G

A/M

    

1011 genomes

51% A/S

67% G/V

    
 

49% G/G

33% A/M

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