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Table 3 Enzymes involved in lipid metabolism in Saccharomyces cerevisiae model, iNL800 [70], Yarrow lipolytica model, iNL895 [37] and Cutaneotrichosporon oleaginosus ATCC 20509 model, iNP636_Coleaginosus_ATCC20509 (this study)

From: Genome-scale metabolic modeling underscores the potential of Cutaneotrichosporon oleaginosus ATCC 20509 as a cell factory for biofuel production

EC Function S. cerevisiae (iNL800) Y. lipolytica (iNL895) C. oleaginosus ATCC 20509
EC 6.2.1.1 Acetyl-coenzyme A synthetase 1 Y
EC 6.2.1.1 Acetyl-coenzyme A synthetase 2 Y Y Y
EC 1.3.1.9 Fatty acid synthase subunit beta Y Y (2) Y
EC 2.3.1.86 Fatty acid synthase subunit alpha Y Y (2) Y
EC 2.7.7.41 Phosphatidate cytidylyltransferase Y Y (2) Y
EC 2.7.8.11 CDP-diacylglycerol–inositol 3-phosphatidyltransferase Y Y Y
EC 2.7.8.8 CDP-diacylglycerol–serine O-phosphatidyltransferase Y Y Y
EC 2.7.1.30 Glycerol kinase Y Y Y (2)
EC 1.1.1.8 Glycerol-3-phosphate dehydrogenase (NAD( +)) Y (2) Y Y (2)
EC 2.3.1.51 Probable 1-acyl-sn-glycerol-3-phosphate acyltransferase Y Y (2) Y
EC 2.3.1.20 Diacylglycerol O-acyltransferase Y Y Y
EC 2.3.1.158 Phospholipid:diacylglycerol acyltransferase Y Y Y
EC 3.1.1.3 Triacylglycerol lipase Y (3) Y (2) Y (2)
EC 2.3.1.26 Acyl-CoA:sterol acyltransferase Y Y Y
EC 1.14.19.1 Acyl-CoA desaturase Y Y Y
EC 1.14.19.6 ∆12 Fatty acid desaturase Y Y
EC 1.3.3.6 Acyl-coenzyme A oxidase Y Y (3) Y
EC 2.3.1.16 3-ketoacyl-CoA thiolase, peroxisomal Y Y Y (2)
EC 2.3.3.8 ATP-citrate lyase, subunit a Y Y
EC 2.3.3.8 ATP-citrate lyase, subunit b Y Y
EC 1.1.1.38 NAD-dependent malic enzyme, mitochondrial Y Y Y
EC 6.4.1.2 Acetyl-CoA carboxylase Y Y Y
  1. Y indicates the presence of the enzyme-encoding gene, (−) indicates the absence of the enzyme-encoding gene. Number of isoenzymes is indicated in brackets