Fig. 1
Model of the biochemistry and bioenergetics of acetogenesis from H2 + CO2 in T. kivui. The bioenergetics and biochemistry of acetogenesis from H2 + CO2 by T. kivui are shown. CODH/ACS, CO dehydrogenase/acetyl-CoA synthase; Ech, energy-conserving hydrogenase; HDCR, hydrogen-dependent CO2 reductase; hydrogenase, electron bifurcation hydrogenase; THF, tetrahydrofolic acid; HCO-THF, formyl-THF; HC-THF, methenyl-THF; H2C-THF, methylene-THF; H3C-THF, methyl-THF; CoFeSP, corrinoid iron–sulfur protein; Fd2−, reduced ferredoxin; * reduction of methylene-THF might occur using an electron donor with a similar redox potential as NADH