Fig. 3From: Coordination of consolidated bioprocessing technology and carbon dioxide fixation to produce malic acid directly from plant biomass in Myceliophthora thermophilaCombined effects of Calvin–Benson–Bassham (CBB) cycle and disruption of branch pathway genes on production of malic acid. a Schematic representation of integration of prk, cbbM, and selective marker gene neo into the ldh, pdc, and pck loci, respectively, of the M. thermophila genome using the CRISPR/Cas9 system. Titers of malic acid produced by strain CP-51 grown on (b) xylose, (c) arabinose, (d) glucose, and (d) Avicel. Titer of malic acid was determined after 8 days of fermentation. The values and error bars represent means and standard deviationsBack to article page