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Table 3 Most significantly differentially expressed transcripts between timepoints T2 and T3 with reaction associations in iDU1327

From: Integration of Aspergillus niger transcriptomic profile with metabolic model identifies potential targets to optimise citric acid production from lignocellulosic hydrolysate

Transcript ID

Effect

Log2FC

Associated reactions in iDU1327

Names of associated reactions

Aspni_transcript.chr_302G588.1

Down-regulated

− 8.9

R719

Uracil phosphoribosyltransferase

Aspni_transcript.chr_302G590.1

Down-regulated

− 7.3

R173

GTP 7,8–8,9-dihydrolase (diphosphate-forming)

Aspni_transcript.chr_401G344.1

Down-regulated

− 4.8

R1176

3-Hydroxy-3-methylglutaryl coenzyme A synthase

Aspni_transcript.chr_202G1142.1

Down-regulated

− 4.6

R193; R198

Alcohol dehydrogenase

Aspni_transcript.chr_802G171.1

Down-regulated

− 4.4

R228; R230; R791; R796; R801; R806; R811; R816; R821; R826; R831; R837; R842; R847; R852; R857; R862; R867; R872

L-Xylulose reductase;3-Oxoacyl-[acyl-carrier-protein] reductase

Aspni_transcript.chr_603G16.1

Down-regulated

− 4.1

R451

ATP synthase

Aspni_transcript.chr_102G146.1

Down-regulated

− 3.7

R791; R796; R801; R806; R811; R816; R821; R826; R831; R837; R842; R847; R852; R857; R862; R867; R872

3-Oxoacyl-[acyl-carrier-protein] reductase

Aspni_transcript.chr_101G224.1

Down-regulated

− 3.3

R322

alpha-amylase

Aspni_transcript.chr_304G378.1

Down-regulated

− 3.2

R791; R796; R801; R806; R811; R816; R821; R826; R831; R837; R842; R847; R852; R857; R862; R867; R872

3-Oxoacyl-[acyl-carrier-protein] reductase

Aspni_transcript.chr_801G344.1

Down-regulated

− 3

R182; R188; R265; R1207; NR14; NR26

Riboflavin-5-phosphate phosphohydrolase; Thiamin monophosphate phosphohydrolase; Phosphatidate phosphatase; 4-Nitrophenyl phosphate phosphohydrolase; Glycerone phosphate phosphohydrolase

Aspni_transcript.chr_304G666.1

Up-regulated

4.8

R211; R1115

Glycerol 3-phosphate dehydrogenase (NAD + dependent)

Aspni_transcript.chr_101G504.1

Up-regulated

4.7

R71; R75; R516

S-(hydroxymethyl)glutathione dehydrogenase; Formaldehyde dehydrogenase; Threonine dehydrogenase

Aspni_transcript.chr_602G271.2

Up-regulated

4.7

R107; R108

Succinate-semialdehyde dehydrogenase

Aspni_transcript.chr_501G182.1

Up-regulated

4.6

R106; R611

4-Aminobutyrate transaminase

Aspni_transcript.chr_102G293.1

Up-regulated

4.5

R107; R108

Succinate-semialdehyde dehydrogenase

Aspni_transcript.chr_202G964.1

Up-regulated

3.8

R153; R479; R604

Adenosyl:methionine-8-amino-7-oxononanoate aminotransferase; Ornithine transaminase

Aspni_transcript.chr_101G108.1

Up-regulated

3.7

R378; R402; R404; R615; NR23

Amine oxidase

Aspni_transcript.chr_402G585.2

Up-regulated

3.7

R33; R34

Phosphoketolase

Aspni_transcript.chr_202G803.1

Up-regulated

3.6

R103; R104

Methylmalonate-semialdehyde dehydrogenase

Aspni_transcript.chr_402G613.1

Up-regulated

3.1

R78

Pyruvate decarboxylase

  1. Transcripts shown have q value < 1E−40 and are ranked by log2FC