Integration of Aspergillus niger transcriptomic profile with metabolic model identifies potential targets to optimise citric acid production from lignocellulosic hydrolysate

Table 8 Tools used in functional annotation of transcripts

Name of tool	References	%Transcripts annotated
KEGG Automatic Annotation Server (KAAS)	[33]	32.6
InterProScan	[34]	71.1
Blast2GO	[35]	56.1
Batch CD-Search against COG database	[36,37,38]	45.9
Batch CD-Search against PFAM database	[36, 37, 39]	68.6
Batch CD-Search against SMART database	[36, 37, 40]	22.1
Batch CD-Search against TIGR database	[36, 37, 41]	30.3
ScanProsite	[42]	35.8
BLASTP search against BRENDA database (thresholds: 60% identify, E-value 1E-6)	[43, 44]	24.1
HAMAP-Scan	[45]	2.6
GOFEAT (threshold: E-value 1E-5)	[46]	66.9
EFICAz^2.5	[47]	19.4
TransAAP	[48]	6.8

ISSN: 2731-3654