Fig. 4
From: Bottom-up synthetic ecology study of microbial consortia to enhance lignocellulose bioconversion
Key factors of design and engineering microbial communities for lignocellulosic conversion. A Microbial cooperation can be designed to perform the task of lignocellulose bioconversion. Computational and mathematical models are effective tools for genome-wide explore task assignment. B Spatial assortment contributes to microbial cooperation to degrade lignocellulose. Biofilms, formed by degraders or producers, provide an interface in which multiple species synergize for lignocellulose conversion. In addition, modified bioreactors can achieve spatial separation for microbial members which have different growth conditions. C Robustness and stability of communities can be maintained by spatial self-organization and regulation of relative cooperator/cheater benefits. D Overview of pipeline for the automated design of synthetic microbial communities [95]. It provides a promising avenue for the effective and easy design of microbial communities for lignocellulosic conversion