Table 1 The genes selected for use in this study

1: transcription

xyr1 (122208)

Transcription activator, verified

OE

cbh1

xyr1

N/A

[15]

ace3 (77513)

Transcription activator, verified

OE

pdc1

pdc1

N/A

[19]

26163

Transcription activator, verified

OE

gpd1

eno1

N/A

[19]

66966

Transcription activator, verified

OE

gpd1

eno1

N/A

[19]

122523

Transcription activator, verified

OE

gpd1

eno1

N/A

[19]

80291

Transcription activator, verified

OE

cDNA1

cDNA1

N/A

[19]

64608

Transcription activator, verified

OE

cDNA1

cDNA1

N/A

[19]

123668

Transcription activator, verified

OE

xpp1

xpp1

N/A

[19]

27600

Transcription activator, predicted

OE

xpp1

xpp1

N/A

[45]

74765

Transcription activator, verified

OE

xpp1

xpp1

N/A

[19]

cre1 (120117)

Transcription repressor, verified

RMGS

cDNA1

N/A

xpp1

[45]

ace1 (75418)

Transcription repressor, verified

RMGS

cDNA1

N/A

xpp1

[58]

2: secretion

sed1 (119975)

Glycosylation, predicted

RMGS

pdc1

N/A

eno1

[13]

der1 (124187)

Protein degradation, verified

RMGS

pdc1

N/A

eno1

[38]

ych1 (68274)

Protein degradation, predicted

RMGS

pdc1

N/A

eno1

[13]

ymr1 (119854)

Protein degradation, predicted

RMGS

tef1

N/A

pki

[13]

och1-2 (80340)

Glycosylation, predicted

RMGS

tef1

N/A

pki

[13]

pep4 (77579)

Protein degradation, verified

RMGS

tef1

N/A

pki

[13]

doa10 (123493)

Protein degradation, verified

RMGS

tef1

N/A

pki

[59]

yps1 (122076)

Protein degradation, verified

RMGS

cDNA1

N/A

xpp1

[13]

3:cell metabolism

80621

Amino acid biogenesis, predicted

OE

gpd1

eno1

N/A

[60]

52055

Amino acid biogenesis, predicted

OE

pki

cbh2

N/A

[61]

53567

Free radical elimination, predicted

OE

cDNA1

cDNA1

N/A

[62]

zwf1 (75769)

NADP/NADPH balance, verified

OE

cDNA1

cDNA1

N/A

[37]

72685

NADP/NADPH balance, verified

OE

cDNA1

cDNA1

N/A

[37]

73903

NADP/NADPH balance, verified

OE

pki

cbh2

N/A

[26]

aox1 (57940)

NAD/NADH balance, verified

OE

xpp1

xpp1

N/A

[47]