Skip to main content
Fig. 1 | Biotechnology for Biofuels and Bioproducts

Fig. 1

From: Acetoin production from lignocellulosic biomass hydrolysates with a modular metabolic engineering system in Bacillus subtilis

Fig. 1

Biotechnological strategies for acetoin production by B. subtilis. This work blocked spore formation at different stages and mitigated autolysis in strains by regulating genes for peptidoglycan hydrolase and cell cannibalism. Subsequently, NADH/NAD+ was regulated by the redox global regulator Rex to optimize the allocation of carbon flux levels, followed by blocking the main pathway of lactate, succinate, and 2,3-butanediol production. Finally, the population cell density-induced promoter enhances the enhancement of α-acetolactate synthase and α-acetolactate decarboxylase. Bold arrows indicate overexpressed genes in this study, and red crosses indicate disrupted genes

Back to article page

Biotechnology for Biofuels and Bioproducts

ISSN: 2731-3654

Contact us