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Table 1 Effects of the different pH values on PQQ fermentation

From: Adaptive evolutionary strategy coupled with an optimized biosynthesis process for the efficient production of pyrroloquinoline quinone from methanol

pH

Time (h)

Biomass (g/L)

PQQ production (g/L)

PQQ yield (mg/g DCW)

PQQ productivity (mg/L × h)

6.0

168

32.3 ± 1.23

0.908 ± 0.0195

28.1 ± 0.603

5.41 ± 0.116

6.5

168

39.6 ± 1.39

1.22 ± 0.0284

30.8 ± 0.717

7.26 ± 0.169

7.0

168

36.4 ± 2.11

1.42 ± 0.0481

39.0 ± 1.321

8.45 ± 0.286

7.5

168

29.4 ± 0.97

0.920 ± 0.0258

31.3 ± 0.878

5.48 ± 0.154

6.5–7.0

144

37.7 ± 1.26

1.52 ± 0.0348

40.3 ± 0.923

10.5 ± 0.242