Fig. 3

Multi-omic analyses of 3-HP production in Aspergillus species. A) Shake-flask cultivation of Aspergillus species engineered to produce 3-HP. B Extracellular metabolites detected and quantified by GC–MS at day four. C Protein and intracellular metabolite levels relative to the un-engineered parent strains at day four. D Targeted peptide quantification of the heterologous pathway proteins at day four. Multiple boxes for a single protein indicate different targeted peptides. The data represent four biological replicates